Sterilization Specifications
In the realm of sterilization, various physical and chemical processes, such as steam sterilization and dry heat sterilization, can be employed. The choice of sterilization method can significantly impact factors like packaging, transportation, and storage conditions. The primary purpose of sterilization is the removal of pathogens.
Steam sterilization is commonly employed for reusable surgical tools, effectively eliminating microbes, including bacterial spores, in approximately 15 minutes. However, it's crucial to note that the presence of water droplets can lead to corrosion. Plastic and electronic medical devices may not be suitable for steam sterilization due to potential damage.
10.4.2 Dry Heat Sterilization
Dry heat sterilization relies on conduction, where heat is absorbed by the exterior surface of an item and gradually transferred to the entire item. This process takes around 30 minutes due to the inefficiencies of heating air with low moisture content. Metal and glass compositions are used in ovens or cages to withstand high temperatures and pressured air. This method is commonly applied to items like vaccines and vials to eliminate microorganisms, requiring a temperature of approximately 180°C for effective neutralization of spores and contamination.
Ethylene oxide sterilization is a chemical process involving gas concentration, humidity, temperature, and time. The interaction of an alkaline agent and ethylene oxide with DNA halts cell growth and divisions, effectively killing microorganisms. This method is suitable for medical devices packed with plastics. While effective, it is important to note that ethylene oxide is highly toxic at low temperatures, requiring a leak-proof chamber for containment. Examples of suitable materials include plastics and electronics.
10.4.4 Radiation Sterilization
Gamma and E-beam radiation are utilized for sterilizing medical devices, particularly those labeled as "single-use." Unlike ethylene oxide, these methods do not leave a trace of radioactivity. However, it's important to be aware that these sterilization methods can penetrate plastic packaging surfaces. Despite their advantages, radiation sterilization may cause cosmetic and functional issues with various materials used in medical devices. Examples include implants and autoinjectors.